However, the latest on Darius Slayton is more grim. Now, the Giants admitted what many feared about the Slayton hamstring injury via social media. It is no secret that the New York Giants are shorthanded going into Thursday night's meeting with the 4-1 Philadelphia Eagles.

Darius Slayton was seemingly due for an uptick in targets and receptions with Malik Nabers out of the equation. However, the wide receiver has run into his own injury troubles.

Per Jeremy Fowler of ESPN, receiver Darius Slayton is set to miss the Week 6 contest with a hamstring injury. Slayton has been listed as a non-participant on each of the Giants' first two injury reports this week. As Fowler notes, hamstring injuries are difficult to recover from on a short week.

Mike Kafka might not have Malik Nabers or Darius Slayton against the Eagles, but he still has confidence in the other receivers.

The New York Giants have ruled out three players ahead of Thursday night’s NFC East clash with the Philadelphia Eagles — including a key playmaker at a position of need. The Giants ruled out wide receiver Darius Slayton (hamstring), as well as linebackers Swayze Bozeman (ankle) and Demetrius Flannigan-Fowles (hamstring) on Wednesday.

Jeremy Fowler of ESPN reports that Giants wide receiver Darius Slayton is set to miss the Week 6 contest against the Eagles with a hamstring injury

Slayton (hamstring) is ruled out for Thursday's game against the Eagles, Dan Salomone of the Giants ' official site reports.

Week 5 fantasy football waiver wire pickups for Darius Slayton, Josh Downs, Christian Kirk in 2025. Read their waiver wire outlooks for fantasy football.

Barring a miracle, Darius Slayton is in danger of missing Thursday's game against the Eagles due to a hamstring injury.