Jim Gaffigan shared his weight loss journey with Mounjaro, as he shed 50 pounds. Celebrities like Rosie O'Donnell and Amy Schumer also credited the diabetes drug.

Comic Jim Gaffigan recently lost 50 lbs. on Mounjaro, joking, "I can’t even take any pride” in it because he relied on ...

Jim Gaffigan opens up about his 50lb weight loss using Mounjaro, sharing insights on feeling better, health benefits and ...

Jim Gaffigan made a bold admission about his weight-loss journey. The 58-year-old confessed that his transformation was less about willpower and more about convenience, as he credited Mounjaro ...

The comic previously told PEOPLE that he wanted to talk about taking the injectable Mounjaro, explaining, "I don't think there's anything wrong with it" Jim Gaffigan riffed about not being able to ...

Jim Gaffigan (left) in 2015; (right) in 2025.