No. 4 Purdue plays No. 1 Houston in the Sweet 16 round of the NCAA Men's Basketball Tournament. Follow the live blog for in-game updates throughout the night.

Watch this Sweet 16 NCAA Tournament matchup between the No. 1 Houston Cougars (32-4) and No. 4 Purdue Boilermakers (24-11) to determine which of the squads is heading to the Midwest Region bracket

Purdue fans were irate with the officials late in Friday's Sweet 16 game in the Boilermakers' heartbreaking 62-60 loss to Houston.

SportsLine's model revealed its college basketball predictions for Houston Cougars vs. Purdue Boilermakers on Friday in the Sweet 16 of the 2025 NCAA Tournament

The Houston Cougars are seeded first in the Midwest Regional and have won 15 consecutive games. Purdue is seeded fourth. Game picks, predictions.

SportsLine expert Micah Roberts has revealed his Purdue Boilermakers vs. Houston Cougars picks for the Sweet 16 of the 2025 NCAA Tournament on Friday

It is not labeled as a home game for Purdue but it may well sound like one when the Boilermakers (24-11) take the court against the Houston Cougars (32-4) in the Sweet 16 Friday, in Indianapolis, IN.

It’s the Purdue Boilermakers vs Houston Cougars in March Madness bracket. Here’s our prediction for the 2025 NCAA Tournament Sweet 16 game.

Purdue’s season ended with a loss but with heads held high. Hear what Purdue forward Cam Heide after the Sweet 16 loss to Houston.