Kickoff from Old Trafford in Manchester is set for 11:30 a.m. ET. The Gunners are -118 favorites (risk $118 to win $100) on the 90-minute money line in the latest Manchester United vs. Arsenal odds, while Man United are +310 underdogs.

Andre Onana sustained a hamstring injury in July and had to sit out the preseason friendly matches. The Cameroonian goalkeeper is reportedly ready return to action in the Red Devils' opening Premier League match.

The opening weekend of the new Premier League season did not disappoint in terms of fixtures, with Manchester United taking on Arsenal.