UnitedHealthcare CEO Brian Thompson was shot and killed in Midtown Manhattan Wednesday morning in a “brazen, targeted attack” as he walked toward the hotel hosting the company’s annual investor conference,

A gunman killed UnitedHealthcare’s CEO on Wednesday in a “brazen, targeted attack” outside a Manhattan hotel where the health insurer was holding its investor conference, police said, setting off a massive search for the fleeing assailant hours before the annual Rockefeller Center Christmas tree lighting nearby.