Elizabeth Jonas first got interested in mitochondria by chance. In 1995, she was a postdoctoral researcher at Yale, working ...

Cold weather triggers brown fat to burn energy, thanks to a newly discovered protein switch. This natural calorie-burning ...

ATP synthase is a universal molecular machine for energy conversion. By coupling to cellular respiration in mitochondria, it catalyzes conversion of chemical energy of cells. Mitochondrial ATP ...

A collaborative study from the University of Cologne has uncovered how a key mitochondrial protein, AIFM1 (Apoptosis-Inducing ...

ATP, the fuel of life, is produced in mitochondria of living cells by a molecular machine, the ATP synthase. Researchers have isolated the machines from four fungal species, compared their ...

ATP synthase is located in the inner membrane of the mitochondria. Where is ATP stored? Once synthesized, ATP is stored inside the mitochondrial matrix or it can be transported into the intermembrane ...

P5CS-containing mitochondria showed higher membrane potential, suggesting that they engage in reductive metabolism for proline and ornithine synthesis, while ATP synthase-enriched mitochondria are ...

Proteomics in Neurodegenerative Diseases: A Focus on Mitochondrial Dysfunction & Oxidative Stress In the last 10 years, proteomic approaches have been largely applied in order to identify which ...

Background. Each year, about 1,000 to 4,000 children in the United States are born with a mitochondrial disease. Many of these diseases are tied to a deficiency in ATP synthase thought to be triggered ...

Through genome sequencing, researchers found a mutation in a particular enzyme known as mitochondrial ATP synthase. Cells need this enzyme to generate ATP, a molecule that is essential to storing ...