The three-dimensional structure of a protein involved in the assembly of actin filaments could help to settle a long-standing scientific debate about the regulation of cytoskeletal organization. The ...

An electron microscopy study revealed key details of actin filaments, which are essential structural elements of cells and muscles. Actin filaments -- protein structures critical to living movement ...

Researchers at Kanazawa University report in eLife on deciphering the actin structure-dependent preferential cooperative binding of cofilin. The actin filament is a double-stranded helical structure ...

Researchers have demonstrated that an actin scaffold stabilizes the cell nucleus upon mechanical stress. This protective ...

Actin filaments - protein structures critical to living movement from single cells to animals - have long been known to have polarity associated with their physical characteristics, with growing ...

Arp2/3 complex nucleates branched actin filaments important for cellular motility and endocytosis. WASP family proteins are Arp2/3 complex activators that play multiple roles in branching nucleation, ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 116, No. 10 (March 5, 2019), pp. 4265-4274 (10 pages) We used cryo-electron microscopy (cryo-EM) to reconstruct ...

For immune cells, the actin cytoskeleton is more than a structural scaffold. Immune cells can migrate to sites of infection ...

Huntington's disease is a rare genetic disorder and a representative neurodegenerative disease, characterized by loss of ...

After the cell has been treated with a messenger substance (right), the green actin molecules in the red cell nucleus (left) form actin filaments that structure the genome. Disclaimer: AAAS and ...

Researchers from the Cluster of Excellence CIBSS have demonstrated that an actin scaffold stabilizes the cell nucleus upon ...