ascopubs.org

Bayesian Adaptive Randomization: Full of Promise With a Helping of Caution

In the article that accompanies this editorial, Rahman et al 2 describe the results from the first three experimental arms of the INSIGhT trial which, to our knowledge, is the first adaptive platform ...
Nature

Adaptive regression model for Parkinson’s disease diagnosis from speech signals using Box-Cox-based clustering and extremely randomization

Parkinson’s Disease (PD) is a progressive neurodegenerative disorder that causes motor and cognitive impairments, affecting approximately 1% of individuals over 60 years of age. Speech impairments are ...
Business Wire

Global Coalition for Adaptive Research Announces Key Updates on GBM AGILE Phase 2-3 Adaptive Platform Trial for Patients With Glioblastoma

LOS ANGELES--(BUSINESS WIRE)--Global Coalition for Adaptive Research (GCAR) today announced an update on the progress of GBM AGILE (Glioblastoma Adaptive Global Innovative Learning Environment - ...
Nature

Androgen receptor pathway inhibitors and taxanes in metastatic prostate cancer: an outcome-adaptive randomized platform trial

Metastatic castration-resistant prostate cancer (mCRPC) is a genetically and clinically heterogeneous disease that can be treated with different classes of systemic agents, such as androgen receptor ...
The American Journal of Managed Care

Reducing Risk and Improving Efficacy of Clinical Trials: the Adaptive Design

A clinical trial is a massive investment for the drug manufacturer—an investment of time, effort, and funds that are channeled into preclinical research to identify a target and the right molecule for ...
ascopubs.org

Bayesian Adaptive Randomization: Full of Promise With a Helping of Caution

The following represents disclosure information provided by the authors of this manuscript. All relationships are considered compensated unless otherwise noted. Relationships are self-held unless ...