Scientists have uncovered new evidence that strengthens the link between a host-cell gene called Apobec3 and the production of neutralizing antibodies to retroviruses. Published in the Sept. 5 issue ...
BKPyV infection is often asymptomatic or mild during childhood, but may leave a lasting impact on cancer risk. In A Nutshell Nearly all adults (95%) carry BK polyomavirus from childhood infections ...
The human APOBEC3 (A3A-A3H) locus encodes six cytidine deaminases that edit single-stranded DNA, the result being DNA peppered with uridine. Although several cytidine deaminases are clearly ...
The APOBEC3 (A3) gene family encodes proteins that can mutate viral genomes by changing cytosines to uracils in single-stranded DNA through a deamination reaction that results in potentially lethal ...
Scientists uncovered how childhood BK virus infections may set off cancer-causing mutations decades later: by activating a host immune system enzyme that attacks DNA.
An enzyme that defends human cells against viruses can help drive cancer evolution towards greater malignancy by causing myriad mutations in cancer cells, according to a new study. The finding ...
Scientists have uncovered new evidence that strengthens the link between a host-cell gene called Apobec3 and the production of neutralizing antibodies to retroviruses. Published in the Sept. 5 issue ...