Probable pitching matchups and start times: LHP Logan Allen (3-3, 4.22) vs. LHP Colton Gordon (0-1, 5.94) Friday at 7:10 p.m.; RHP Gavin Williams (5-3, 3.79) vs. RHP Hunter Brown (8-3, 1.83) Saturday at 4:10 p.m. and RHP Tanner Bibee (4-6, 3.89) vs. RHP Lance McCullers Jr. (1-1, 4.44) Sunday at 1:40 p.m.

The Astros are 34-28 with a +21 run differential, 14th in team wRC+ at 102, 15th in baserunning runs above average at -0.3, eighth in Defense at -0.8, second in starting pitcher SIERA at 3.55, and third in bullpen SIERA at 3.

Pregame analysis and predictions of the Houston Astros vs. Cleveland Guardians MLB game to be played on June 6, 2025 on ESPN.