With the ever-increasing pace of biological research, there is a plethora of headlines describing novel and fascinating discoveries about our natural world. What’s easy to overlook, however, is the ...

Anna Z. Wec, Denise Haslwanter, Yasmina N. Abdiche, Laila Shehata, Nuria Pedreño-Lopez, Crystal L. Moyer, Zachary A. Bornholdt, Asparouh Lilov, Juergen H. Nett ...

With machine learning methods and an advanced technique called lattice light sheet microscopy (LLSM), scientists have now revealed structures on the surface of B cells that influence how those immune ...

Recognition of antigens is prompt and specific. But should a T cell initiate an unstoppable chain reaction of destruction against the intruder? Is it an intruder at all? It all depends on the ...

However, details of the intervening steps, as researchers have learned in the past 65 years, are quite complex — certain cells carry the flu antigen to the immune system, specific immune cells respond ...

Although CAR T-cell therapies have reached significant clinical success in hematological malignancies, their utility in solid tumors remains limited. One of the main challenges is the scarcity of ...

To date, treatment with LEU011 has been generally well tolerated. In addition, disease control (based on RECIST criteria) has been observed in multiple patients treated with the lowest dose of LEU011.