Downstream bioprocessing steps have long been a challenge to drug manufacturers, particularly the chromatography step for purification of monoclonal antibodies (mAbs). The complexity of traditional ...

Chromatography in Greek means to ‘write with colors.’ It is a versatile separation technique developed in 1903 by Mikhail Tswett, a Russian botanist. He separated colorful plant pigments using a ...

Please can you give us a brief overview of the miniaturization of columns in chromatography? The miniaturization of columns in chromatography originated with the theoretical work of Marcel Golay on ...

Reviewed by Dr. Catherine Shaffer, Ph.D. Chiral column chromatography makes use of the concept of chirality. Chirality relates to study of the three-dimensional structure of molecules. The term comes ...

The history of chromatography begins during the mid-19th century when a rudimentary version of the technique was used for the separation of plant pigments such as chlorophyll. The first chromatography ...

High performance liquid chromatography (HPLC) is a separation technique that uses liquid mobile phase to separate the components of a mixture. The sample is first dissolved in a solvent, then forced ...