Although distinct in structure and function, cohesin and condensin both contain conserved chromosomal ATPases of the structural maintenance of chromosomes (SMC) protein family. Present models indicate ...

The condensin complex is essential for correct packaging and segregation of chromosomes during mitosis and meiosis in all eukaryotes. To date, the genome-wide location and the nature of ...

Scientists have identified how a specific variant of a key protein complex found in human cells called condensin can reorganize a cell's genetic architecture in such a way as to promote senescence, ...

This study is led by Dr. Yue Zhou (State Key Laboratory of Gene Function and Modulation Research, School of Advanced Agricultural Sciences, Peking-Tsinghua Center for Life Sciences, Peking University, ...

Advances in our understanding of basic biological processes and human disease owe much to the groundbreaking research of scientists at the Chromosome Dynamics Laboratory at RIKEN Advanced Science ...

A living cell is able to neatly package a big jumble of DNA into chromosomes while preparing for cell division. For over a century, scientists have been puzzled for decades on how the process works.

The most accurate quantitative model yet for understanding the role of condensin during cell division is also visually stunning. A team of scientists from UT Austin have developed the most accurate ...

The paper M. Ganji et al., “Real-time imaging of DNA loop extrusion by condensin,” Science, doi:10.1126/science.aar7831, 2018. How does a human cell neatly pack ...

During quiescence, cells cease to proliferate and enter a state of dormancy where they are resistant to stressors and can survive long-term. In quiescent cells, global gene expression is decreased by ...

Remarkably, living cells are able to package a jumble of DNA over two meters in length into tidy, tiny chromosomes while preparing for cell division. However, scientists have been puzzled for decades ...

It's so impressive: a living cell is able to neatly package a big jumble of DNA, over two meters in length, into tidy, tiny chromosomes while preparing for cell division. For over a century, it has ...