Inspired by long-lived animals — and human centenarians — researchers are hunting for ways to enhance DNA repair and extend ...

Our DNA is under constant threat. Chemicals, radiation and the everyday errors of cell division all damage it, and if left unrepaired, this can lead to diseases such as cancer. Cells invest heavily in ...

When a wound does not heal properly, it leaves a scar. Similarly, mutations—which are permanent changes to genetic code—are ...

A new fluorescent sensor is giving scientists an unprecedented view of how cells respond to DNA damage, capturing the repair process as it unfolds in real time. The tool, developed at Utrecht ...

A new way for hard-to-treat cancer cells to protect themselves from being killed by anticancer drugs has been found. The ...

A research team from the University of California (UC), Irvine, has revealed a previously unknown mechanism that triggers an inflammatory immune response in cells when their DNA is damaged. The ...

A previously unknown type of DNA damage in the mitochondria, the tiny power plants inside our cells, could shed light on how our bodies sense and respond to stress. The findings of the UC ...

Similar to the way DNA damage can contribute to human diseases such as cancer, it can also disrupt growth, development and survival in plants. Every day, plants endure environmental stresses such as ...

Cancer cells rely on powerful genetic switches to keep growth genes running at full speed, but that intense activity can damage their own DNA. The resulting breaks are repeatedly repaired, sometimes ...

The cancer drugs called PARP inhibitors have a puzzling reputation: even though they are treatment mainstays for multiple forms of cancer, they can damage cancer-killing T cells and disrupt the ...

Bedient, a reproductive endocrinologist at the Fertility Center of Las Vegas, had already ordered the usual battery of tests, ...