Nature

Rescue administration of a helper-dependent adenovirus vector with long-term efficacy in dogs with glycogen storage disease type Ia

Glycogen storage disease type Ia (GSD-Ia) stems from glucose-6-phosphatase (G6Pase) deficiency and causes hypoglycemia, hepatomegaly, hypercholesterolemia and lactic acidemia. Three dogs with GSD-Ia ...
Medscape

Hemophilia B: Lentiviral Vector Safe, Effective in Dogs

Lentiviral vectors effectively deliver the gene that encodes coagulation factor IX (FIX) to the liver in dogs with naturally occurring hemophilia B (factor IX deficiency), researchers report in an ...
Science Daily

Hunting dogs as possible vectors for the infectious disease tularaemia

Tularaemia is an infectious bacterial disease that is life-threatening for rodents, rabbits and hares, but which can also infect humans and dogs. While contact with contaminated blood or meat makes ...
JSTOR Daily

Immunity of Dogs against Babesia canis, Its Vector Tick Dermacentor reticulatus, and Ixodes ricinus in Endemic Area

Previous epidemiological studies allowed us to accurately define endemic areas of canine babesiosis and tick distribution in southeastern France (Martinod, 1983). Using a micro-ELISA test 100 dogs ...
Nature

Restoration of vision in RPE65-deficient Briard dogs using an AAV serotype 4 vector that specifically targets the retinal pigmented epithelium

Inherited retinal dystrophies are a heterogeneous group of disorders that nearly always share one critical feature, degeneration of photoreceptors. Retinal dystrophies often lead to blindness and ...