Global drug use and the number of drugs on the market have been increasing in the past decades. The century-long dominance of heroin in illicit global opioid markets is increasingly being challenged ...

Drug and substance abuse continues to be a major problem across the United States, with 1 in 4 Americans over the age of 12 admitting that they used illicit drugs in 2022. 1 While alcohol, tobacco and ...

Remarkable scientific progress over the past five decades has helped us develop knowledge of how drugs of abuse induce pleasure, reinforce use, and lead to the compulsive self-administration we call ...