Nature

Side effects associated with the use of dexamethasone for prophylaxis of delayed emesis after moderately emetogenic chemotherapy

The role of dexamethasone to reduce delayed emesis following highly emetogenic chemotherapy is proven, but there is less evidence of benefit after mild–moderately emetogenic regimens. Here, we develop ...
ascopubs.org

Prevention of Cisplatin-Induced Emesis by the Oral Neurokinin-1 Antagonist, MK-869, in Combination With Granisetron and Dexamethasone or With Dexamethasone Alone

Adenovirus-Mediated Wild-Type p53 Gene Transfer in Patients Receiving Chemotherapy for Advanced Non–Small-Cell Lung Cancer: Results of a Multicenter Phase II Study METHODS: This multicenter, ...
The New England Journal of Medicine

Antiemetic Prophylaxis for Chemotherapy-Induced Nausea and Vomiting

5-HT 3 denotes 5-hydroxytryptamine type 3, and NK 1 neurokinin-1. Chemotherapy-induced nausea and vomiting is also associated with operant conditioning, such that unrelated stimuli may induce the ...
ascopubs.org

Oral ondansetron for the control of cisplatin-induced delayed emesis: a large, multicenter, double-blind, randomized comparative trial of ondansetron versus placebo.

Persistence of efficacy of three antiemetic regimens and prognostic factors in patients undergoing moderately emetogenic chemotherapy. Italian Group for Antiemetic Research. Five hundred thirty-eight ...
The New England Journal of Medicine

Chemotherapy-Induced Nausea and Vomiting

The supportive care of patients receiving antineoplastic treatment has dramatically improved over the past two decades. The development of effective means to prevent nausea and vomiting arising from ...