Molecular docking studies represent a cornerstone in modern drug discovery by providing detailed insights into the specific interactions between bioactive compounds and target enzymes. This ...
3D structure of a melanoma cell derived by ion abrasion scanning electron microscopy [National Cancer Institute (NCI). Image created by Sriram Subramaniam, NCI] Researchers at Sanford Burnham Prebys ...
Kinetics for the inhibition of glutamine synthetase (EC 6.3.1.2) in situ by the herbicidal glutamate analogue, phosphinothricin, have been generated, and produce an inhibitor dissociation constant (Ki ...
Putting the brakes on an enzyme might rescue neurons that are dying due to a type of Parkinson’s disease that’s caused by a single genetic mutation, according to a new Stanford Medicine-led study ...
In a new study published in Science Signaling titled, “Restoration of striatal neuroprotective pathways by kinase inhibitor treatment of Parkinson’s linked-LRRK2 mutant mice,” researchers from ...
In our bones, specialized cells called osteoblasts are responsible for building up bone substance. A team of researchers led by scientists from the DKFZ-Hector Cancer Institute at the University ...
Heparin is widely used as an anticoagulant, but evokes in some patients a potentially life-threatening condition called HIT. Clinical scientists at Ludwig-Maximilians-Universitaet (LMU) in Munich have ...
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