Glycosylation is one of the most abundant of all protein post-translational modifications (PTMs). It results from the addition of sugar residues to protein sidechains to form a glycoprotein. Mammalian ...

Glycans are important complex carbohydrates found on cell surfaces that serve crucial roles in cell-to-cell communication, structure, and protection. They are attached to many proteins in the body, ...

Glycosylation May Be Seen as a Way to Enhance or Attenuate Pharmacology Certain words and phrases—quality, safety, process optimization—will almost surely put you to sleep, unless you care about ...

Australian researchers at the Walter and Eliza Hall Institute of Medical Research (WEHI) in Melbourne have developed new yeast- and antibody-based methods to determine how tryptophan C-mannosylation, ...

RIT Assistant Professor Stefan Schulze’s lab is working toward new biomedical treatment approaches through NIH research in ...

A new study by researchers from Taiwan and the US suggests that the removal of unnecessary glycans from spike glycoprotein of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) exposes ...

Furthermore, the scientists expressed spike protein (similar to vaccine candidate) in mammalian cells and compared its glycosylation process with the virus-derived spike protein. Interestingly, the S1 ...

A research team has successfully identified and produced the first recombinant mucin protein derived from the Edible-nest Swiftlet Aerodramus fuciphagus (AfMuc). The study provides insights into the ...

The amyloid precursor protein is processed differently by an alteration in their glycosylation that leads to increased production of beta amyloid, the trigger pathological effector for Alzheimer's ...