Osteochondral defects, often caused by injury or various pathologies, typically lead to the onset of osteoarthritis, and may ultimately result in the comprehensive degradation of the joint and ...

Perlecan is a large heparan sulphate proteoglycan integral to the assembly, maintenance and mechanical responsiveness of cartilage. During embryonic and postnatal cartilage development, perlecan ...

Cartilage is a type of connective tissue found in the body. When an embryo is developing, cartilage is the precursor to bone. Some cartilage remains and is dispersed throughout the body, especially to ...

Cranky knees and other joint pains are normal in the elderly and sometimes even in the young. While these pains are rarely life threatening, those who have them know the burden and effect on quality ...

A microscropy image of the new biomaterial. Nanofibers are pink; hyaluronic acid is shown in purple. (Samuel I. Stupp/Northwestern University) (CN) — Scientists at Northwestern University created a ...

A textile-based implant containing cartilage derived from stem cells reduced pain and restored hip joint function to baseline levels in a study of dogs with symptoms of moderate osteoarthritis. A ...

This study is led by Prof. Yingfang Ao, Prof. Jianquan Wang and Dr. Xiaoqing Hu (Beijing Key Laboratory of Sports Injuries, Institute of Sports Medicine of Peking University, Peking University Third ...