This year’s Lasker Basic Medical Research Award recognizes the contributions of Drs. Richard Hynes, Erkki Ruoslahti, and Timothy Springer for their discovery and characterization of integrins, a major ...

Pfizer's integrin αvβ6-targeting Antibody-Drug Conjugate (ADC) candidate, Sigvotatug Vedotin (PF-08046047, also known as SGN-B6A), has progressed to Phase III clinical trials for PD-L1 high-expressing ...

The BEACON study used de-identified data from the Tempus Database, assessing IB6 expression via immunohistochemistry.

The immune system plays a dual role in inflammation and cancer development. Immune system effector cells quickly identify and destroy malignant cells, but immune system-mediated inflammation regulates ...

Investigating clinical associations between genomic alterations and prostate cancer lineage states using circulating tumor cell RNA sequencing. This is an ASCO Meeting Abstract from the 2025 ASCO ...

Crizanlizumab does not affect mortality or the number of days free of respiratory or cardiovascular (CV) organ-support measures in hospitalized patients with COVID-19. A humanized monoclonal antibody ...

Using single-cell transcriptomic analysis, the team discovered that elevated Selp triggers a pro-inflammatory state within ageing HSCs. This shift activates major cellular pathways linked to ageing ...

The immune system plays a dual role in inflammation and cancer development. Immune system effector cells rapidly recognize and kill malignant cells; meanwhile, immune system-mediated inflammation ...