An immune factor released by white blood cells during infection or inflammation works to suppress the body's immune response instead of enhancing it, according to Mater researchers. The finding gives ...
Intestinal epithelial cells line the inner wall of the gut, creating a barrier to dangerous bacteria like enteropathogenic E. coli that seek to attach and efface that barrier, causing diarrhea. Such ...
Phase 1 study of CB-839, a small molecule inhibitor of glutaminase (GLS), alone and in combination with everolimus (E) in patients (pts) with renal cell cancer (RCC). This is an ASCO Meeting Abstract ...
Intestinal epithelial cells line the inner wall of the gut, creating a barrier to dangerous bacteria like enteropathogenic E. coli that seek to attach and efface that barrier, causing diarrhea. Such ...
NEW YORK — Already in late-stage clinical trials, temtokibart, an interleukin (IL)-22 inhibitor, has demonstrated broad activity against multiple markers of inflammation, pruritus, and impaired ...
In a study published in the journal Immunity, Carlene L. Zindl, Ph.D., and Casey T. Weaver, M.D., of the University of Alabama at Birmingham Department of Pathology show how two types of immune cells ...
The study, “A nonredundant role for T cell-derived interleukin 22 in antibacterial defense of colonic crypts,” was published in Immunity. The team, led by Carlene L. Zindl, Ph.D., found that IL-22 ...
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