Hormone deficiency makes the brain more flexible than expected

Erythropoietin (EPO) is primarily known to many as a hormone for blood formation. However, it has been known for some years ...
JSTOR Daily

Structural instability and divergence from conserved residues underlie intracellular retention of mammalian odorant receptors

Mammalian odorant receptors are a diverse and rapidly evolving set of G protein-coupled receptors expressed in olfactory cilia membranes. Most odorant receptors show little to no cell surface ...
News Medical on MSN

AI Reveals Bitter Taste Receptors’ Hidden Role in Gut-Brain Health

Researchers used AlphaFold3, the latest AI-based protein modeling system, to predict the structures of all 25 known human ...
The Scientist

G Protein-Coupled Receptors and Their Role as Drug Targets

G protein-coupled receptors (GPCRs) are expressed on the surface of cells and regulate a range of important functions. Because they are involved in so many sensory and physiological processes, ...
News Medical

Targeting intracellular checkpoints to enhance NK cell immunotherapy

Natural killer (NK) cells are pivotal in the innate immune response against cancer and viral infections, with their presence in tumors correlating to better patient outcomes in various cancers.
GEN

Bitter Taste Receptor Engages Compounds Not Just Outside the Cell, but Inside

A bitter taste receptor, TAS2R14, has been shown to respond to both extracellular and intracellular signals. Indeed, it can respond to both signals simultaneously. This finding is especially ...