Anti-sense oligonucleotides (ASOs) are short, modified, single-stranded oligonucleotides—made from DNA or locked nucleic acid (LNA)—with enhanced stability, activity, and bioavailability. They ...

A recent study involving researchers from the University of Basel reveals that slowing down the intracellular transport of RNA-based drugs can significantly enhance their effectiveness. These ...

Molecular motors, including proteins such as dynein and kinesin, are essential for the dynamic and regulated movement of cargos along the cytoskeletal network within the cell. These motors convert the ...

In a study now published in Nature Plants, Dr. Yihong Feng (Specially Appointed Assistant Professor) and Professor Takashi ...

Associate Scientific Director Neurosciences and Cellular and Structural Biology Division (NCSBD) Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) National ...

Mercury Bio ( a drug delivery company leveraging its novel and proprietary extracellular vesicle (EV) drug encapsulation platform (yEV™) to transport therapies directly to cells via a unique form of ...

Prof. Fang-Jen S. Lee's team at National Taiwan University has discovered that an intermediate cellular metabolism molecule, glycerol, regulates the localization and function of the Golgi protein Imh1 ...

For immune cells, the actin cytoskeleton is more than a structural scaffold. Immune cells can migrate to sites of infection ...

A team has clarified how in plants the boric acid channels, the conduits for the necessary element boron, are transported to the plasma membrane. Botanists have come to understand the channels and ...

Botanists have come to understand the channels and transporters involved in the uptake and transport of nutrients, yet how are they positioned where they need to be? For example, plants need boron, ...

Metronidazole exerts antibacterial effects in an anaerobic environment against most obligate anaerobes. Once metronidazole enters the organism by passive diffusion and activated in the cytoplasm of ...