Background An 18-year-old Somali man presented to a primary care clinic to investigate a potential pathophysiological reason for behavioral problems at school that had arisen in the past 1–2 years. A ...

Klinefelter syndrome, also known as XXY syndrome, is a genetic disorder that involves an additional X sex chromosome in males. Physiologically, males inherit one X chromosome from their mothers and ...

Brandon Urban and his 13-year-old son, Ben, joke with each other while playing a game of FIFA soccer on Nintendo Wii at their Lawrence home on a recent day. Ben was recently diagnosed with Klinefelter ...

A 54-year-old man of Persian origin presented to our department with a 1-year history of ulcers on the right leg that had been unresponsive to numerous topical treatments, accompanied by lymphedema of ...

In a research partnership between King Abdullah University of Science and Technology (KAUST), King Abdulaziz University, Jeddah (KAU), and King Abdulaziz University Hospital, Jeddah (KAUH), scientists ...

How does an extra X chromosome lead to infertility in men? Professor Qiao Jie and her team at Peking University Third Hospital revealed why Klinefelter syndrome, a common genetic condition affecting ...

Objectives This scoping review identifies existing registries collecting data on Klinefelter’s syndrome (KS) patients and ...

Klinefelter syndrome (47,XXY) is the most common male sex chromosome aneuploidy, affecting approximately 1 in 500–1,000 live male births. Clinically, it is characterised by testicular dysgenesis, ...

When Stephanie Nicklow was pregnant with her son, Theodore, she went in for standard non-invasive prenatal testing (NIPT), but when the results came back, her "entire world shattered." The test came ...

A diagnosis of Klinefelter syndrome can be made based on a number of physical characteristics and symptoms, and confirmed with diagnostic chromosomal analysis. Unlike several other congenital ...