THE investigations of Castle and co-workers 1–6 over the past quarter century strongly support the thesis that pernicious anemia is the result of a gastric defect manifested by an inadequate ...

THE daily dietary requirement for folic acid is unknown, as is the minimal dose of folic acid that will induce hematologic response in a patient with folic acid deficiency. However, it has recently ...

October 24, 2011 — In nonstraightforward bone marrow analysis, the presence of 30% or more CD34+ megakaryocytes is a strong indicator of megaloblastic anemia or a myeloid neoplasm, according to a ...

Megaloblastic anaemia in children is mainly due to folate or vitamin B12 (Vit B12) deficiency. Inherited causes of Vit B12 malabsorption can be related to (1) a lack or low secretion of gastric ...

Doctor Kumar Shital verified that in megaloblastic anaemia the bone marrow produces abnormally large and immature red blood cells. "Megaloblastic anaemia is caused by too little vitamin B12 (cobalamin ...

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Vision – To be the world's leading and most trusted provider of information and services that will make a real difference in clinical practice and improve outcomes for patients. Mission – To lead the ...

DEAR DR. ROACH: I am 71 years old and was diagnosed with pernicious anemia in October 2024. My B12 and folate levels were low. My antiparietal antibodies were abnormal, but the intrinsic factor ...