Blocking the JNK pathway eased disease severity and extended survival in SMA mice, pointing to a potential new treatment approach.

Stroke and spinal cord injuries can severely impair motor functions, and understanding how to promote recovery is a critical challenge. While damaged neurons in the brain and spinal cord have limited ...

In a recent study published in Nature Neuroscience, a group of researchers explored how the cerebellum directly affects dopamine release in the substantia nigra compacta (SNc). While the cerebellum's ...

Here, we report that glycolysis controls astrocyte-synapse contact. In the Drosophila larval dopaminergic (DAergic) circuit, blocking astrocyte glycolysis stimulated perisynaptic ensheathment by ...

A new study identifies a neuronal circuit from the motor cortex to the insular cortex, offering a new target for non-invasive ...

A research team has revealed that a molecule in the brain -- ophthalmic acid -- unexpectedly acts like a neurotransmitter similar to dopamine in regulating motor function, offering a new therapeutic ...