The First Four has been around since 2011 and features the last four automatic qualifiers and last four at-large bids playing to whittle the field from 68 to 64. This year will see two 16-seed vs. 16-seed matchups and two 11-seed vs. 11-seed matchups, but don’t write these games off because they involve double-digit seeds.

The second day of the 2025 NCAA Tournament is almost underway, and the two First Four matchups from Dayton, Ohio, will provide fireworks before Thursday's main event. No. 16 seeds Mount St. Mary's and American face off to start the day,