For the first time, researchers have successfully used computational simulations to modify an enzyme’s structure to increase the optimum temperature of a reaction. Researchers at Uppsala University ...

For the first time, researchers have succeeded in predicting how to change the optimum temperature of an enzyme using large computer calculations. A cold-adapted enzyme from an Antarctic bacterium was ...

Cells must produce energy despite changing conditions. But what keeps metabolic enzymes functional during temperature ...

Deep beneath the ocean surface, at hydrothermal vents where water reaches boiling point, microscopic archaea are quietly ...

Life has evolved over billions of years, adapting to the changing environment. Similarly, enzymes—proteins that speed up biochemical reactions (catalysis) in cells—have adapted to the habitats of ...

Enzymes evolved to efficiently operate in low-temperature environments via key substitutions of amino acids in their active site, which lowers the activation energy of catalytic reactions. Life has ...

A research team has successfully engineered a novel PET hydrolase enzyme, PET2-21M, achieving a remarkable improvement in the biodegradation of bottle-grade polyethylene terephthalate (PET) plastics.

Addressing the global plastic waste crisis, particularly hard-to-recycle blended PET fibers, demands environmentally friendlier recycling methods. Researchers engineered a novel PET hydrolase PET2-21M ...