Diet is among the most important factors contributing to intestinal homeostasis, and basic functions performed by the small intestine need to be tightly preserved to maintain health. Little is known ...

In the study, published in the journal Nature Medicine, the researchers report that defective signaling for a protein called the peroxisome proliferator-activated receptor-γ (PPAR-γ) accounts for a ...

The metabolic syndrome is by now unequivocally established in the minds of endocrinologists as a common and burgeoning disease linked to premature atherosclerosis and cardiovascular disease. Many ...

Natural killer T (NKT) cells maintain the immune system's balance between destruction and tolerance, a mechanism that is off kilter in autoimmune diseases such as type 1 diabetes and irritable bowel ...

In a study that could lead to new therapeutic targets for patients with the cystic fibrosis, scientists have identified a defective signaling pathway that contributes to disease severity. In a study ...