Researchers conducted a retrospective cohort study of 114 patients (68% female; median age at onset, 8.3 years; 92% White) with juvenile localized scleroderma from the National Registry for Childhood ...

A number of studies published over the past 10 years have examined the long-term health, functional and quality of life outcomes of adults with childhood-onset rheumatic diseases such as juvenile ...

Please provide your email address to receive an email when new articles are posted on . All children suspected of having localized scleroderma should be referred to a specialized pediatric ...

Scleroderma is a rare autoimmune condition in which the regulation and deposition of collagen is impaired, causing inflammation and fibrosis (thickening and scarring of connective tissue) throughout ...

We were unable to process your request. Please try again later. If you continue to have this issue please contact customerservice@slackinc.com. Methotrexate and mycophenolate mofetil similarly ...

Scleroderma is a range of disorders in which the skin and connective tissues tighten and harden. It is a long-term, progressive disease. This means it gradually gets worse. Share on Pinterest ...

Systemic sclerosis (SSc), or scleroderma, is a chronic, multisystem autoimmune rheumatic disease characterized by exaggerated fibrosis, vasculopathy, and derangements of the immune system. When ...

Sclerodactyly is a tightening and thickening of the skin of the fingers as a result of systemic scleroderma. It can cause the fingers to curl inward and the hands to form a clawed shape. Share on ...