Virology researchers have found that a specific protein modification to the immune protein MDA5 is key to how our bodies detect and respond to viruses and viral replication. The publication explains ...

A new study on fatty acid acylation, or attachment, patterns onto proteins in Caenorhabditis elegans, a type of roundworm, provides a foundation for future discoveries around protein function and its ...

Exploring the post-translational modifications of a key protein in Parkinson's disease, researchers uncover potential pathways for future therapies in neurodegenerative diseases in general.

In their study, the researchers show that NAC brings two enzymes to the ribosome to first remove the first amino acid from the histone protein and then to modify the newly exposed end with an acetyl ...

N-terminal acetylation represents one of the most ubiquitous protein modifications in eukaryotic cells, with significant implications for protein stability, folding, and interactions. This covalent ...

Cleveland Clinic virology researchers have found that a specific protein modification to the immune protein MDA5 is key to how human bodies detect and respond to viruses and viral replication. This ...

A team at UT Southwestern Medical Center has identified a structural trick that lets viruses translate their genetic code inside human cells, even when that code is riddled with “bad” codons the host ...

Protein AMPylation represents a specialised post‐translational modification (PTM) in which an adenosine monophosphate (AMP) moiety is covalently attached to specific amino acid residues on target ...

Boston College researchers have used a mild charge of electricity to precisely modify proteins—a new and inexpensive tool that can be used to develop novel biotherapeutics and protein-based research ...

Neurodegenerative diseases, such as Alzheimer’s and Parkinson’s, present a significant health challenge, affecting over 50 million people globally. One common feature of these diseases is the ...