RNA silencing processes result in the sequence-specific degradation of RNA and effective post-transcriptional gene silencing. In the May 17 Science, Hongwei Li and colleagues from the University of ...

Two complementary studies led by researchers from the Yong Loo Lin School of Medicine, National University of Singapore (NUS ...

Viroid replication generates dsRNA intermediates, which are processed by Dicer into 21- to 25-nucleotide siRNAs. These siRNAs are then incorporated into siRNA – ribonuclease complexes (RISC). If the ...

Researchers have found a new way to reactivate fetal hemoglobin without the need for gene-editing therapy, according to a new study.

In the past decade, the idea that RNA is just a passive carrier of information has been overturned. Small non-coding RNA molecules are now known to be important regulators of gene expression and ...

A research team from the University of Cologne and collaborators has now shown that RNA interference, or RNAi for short, which is known to be a viral defense mechanism, also prevents the ...

The discovery of siRNA and its role in RNAi was a groundbreaking finding in the field of molecular biology. In 1998, Andrew Fire and Craig Mello published a seminal paper describing the phenomenon of ...

As key players of gene regulation in many bacteria, small regulatory RNAs (sRNAs) associated with the RNA chaperone Hfq shape numerous phenotypic traits, including metabolism, stress response and ...

Scientists at St. Jude Children's Research Hospital and Northwestern University identified a previously unknown treatment ...

O, that these too too solid tissue samples were free of cross-linked, fragmented, and otherwise degraded RNA. Or that tissue RNA analysis techniques were better at coping with miniscule samples or ...