Ever since the discovery of DNA’s double-helix structure, life scientists have been interested in somehow introducing foreign nucleic acid molecules into a host cell and expressing the genes encoded ...

In scientific terms, transfection represents a type of macromolecule delivery in which large, negatively charged polymers (DNA, RNA) are delivered through cellular membranes and into the intracellular ...

Transfection alters the genetic makeup of eukaryotic cells by introducing foreign nucleic acids, including DNA, RNA, and small noncoding RNAs such as siRNA, shRNA, and miRNA. Scientists use ...

This approach holds promise for treating a wide range of diseases, from cancers and genetic disorders to viral infections. Unlike traditional drugs that act on proteins after they’re made, RNA ...

If you work in a lab, whether you are researching the cutting edge of cell and gene therapy development or running a simple molecular binding screen, the chances are you have done some transfection in ...

Bioengineers at the University of California San Diego have developed a powerful new technology that can map the entire network of RNA-protein interactions inside human cells—an achievement that could ...

The Dharmacon™ Edit-R™ Gene Engineering System is a novel platform for research which creates permanent and heritable gene disruption (knockouts) in cells utilizing the CRISPR-Cas9 gene engineering ...

Gene therapy offers the possibility of addressing cancer at its molecular roots by targeting disease-causing genes rather than relying solely on surgery, chemotherapy, or radiotherapy. Among RNA-based ...

Demonstrated feasibility of effective DNA delivery with Company's xPhore™ nanoparticle technologyDNA delivery technology to ...