One of biology's fundamental questions is how our genes shape who we are. Adrian Serohijos and Stephen Michnick, professors in the Department of Biochemistry and Molecular Medicine at Université de ...

A new study finds the proteins responsible for controlling which genes are expressed in a genome do more than simply turn a gene on or off. Essentially, each type of protein that interacts with a gene ...

A protein that's essential to every cell's ability to turn off unnecessary genes is well known for its key function of compacting genes and its connection to cancer when it undergoes mutation. But ...

A new study finds the proteins responsible for controlling which genes are expressed in a genome do more than simply turn a gene on or off. Essentially, each type of protein that interacts with a gene ...

A new study identifies the RNA-binding protein HuR as a repressor of tau exon 10 splicing and a regulator of ...

Duchenne muscular dystrophy has long presented gene therapists with a deceptively simple question: how much dystrophin does a ...

The clues, they say, lie in the murky space between genes and disease — where key proteins come together and interact. A team of researchers from UC San Francisco mapped more than a thousand ...

DNA can be more than just a double helix. When four strands are folded into a compact bundle, they form a G-quadruplex (G4). These bundles form in guanine-rich regions across the genome, including ...

Around 25 million Americans have a rare genetic disease, and many of them struggle with not only a lack of effective treatments, but also a lack of good information about their disease. Clinicians may ...