Summary of the research: This study revealed that T cells can discriminate between self- and neoself- antigens, and that neoself-reactive T cells are involved in causing autoimmune diseases. Osaka, ...
Researchers discovered an entirely new and unexpected mechanism by which the immune system can get rid of cells lacking molecules that identify them as part of the self in mice. The finding has ...
It is well known that the biggest genetic risk factor for the autoimmune disease systemic lupus erythematosus (SLE) is major histocompatibility complex class II (MHC-II). What remains unclear is the ...
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