Stuart Orkin and Swee Lay Thein shared a Breakthrough Prize in Life Sciences for their research on genetic causes of sickle ...

Learn how to exercise safely with sickle cell disease, including recommended activities, precautions to avoid crises, and ...

A reduced-intensity bone marrow transplant regimen developed by Johns Hopkins physicians provides durable engraftment with ...

How is it that you’re alive? It’s a question that we rarely ask ourselves—but it’s one that has a definite answer. We all know our heart pumps life-giving oxygen throughout our bodies. How does that ...

Sickle cell thalassemia occurs when you inherit both a sickle cell gene mutation and a thalassemia gene mutation. Symptoms are similar to other types of sickle cell disease but can vary depending on ...

Sickle cell disease is inherited at birth when you receive related genes from both parents. One gene usually causes sickle cell trait (SCT), which often has no health problems. The main sickle cell ...

Learn about the groundbreaking gene therapy for sickle cell disease at Manning Family Children's Hospital in Louisiana, ...

Sickle cell disease (SCD) can affect people of any ethnicity but is much more common among Africans and African Americans. Other ethnic groups with higher rates of SCD include Hispanic Americans from ...

Sickle cell disease (SCD) is a group of genetic blood disorders. A person inherits SCD from their parents when they inherit two copies of the sickle cell gene, one from each parent. This hereditary ...