Using artificial intelligence, researchers show how γ-secretase recognizes substrates - an important advance for fundamental and translational research. The γ-secretase enzyme is capable of cleaving ...

Alpha-glucosidases are a diverse class of enzymes that catalyse the hydrolysis of α-d-glucosidic linkages at the non-reducing ends of substrates, thereby releasing α-glucose. These enzymes are ...

image: Enzyme substrate specificity involving material conversion processes is pertinent to e.g. biochemistry, metabolic engineering, and environmental remediation; however, it is one of the most ...

Researchers have found a new enzyme, taken from Flavobacterium akiainvivens, that has a much broader specificity than the current leading alternatives. This analysis resulted in the identification of ...

A team of scientists from the United States has recently defined the substrate envelop of the main protease of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The study is currently ...

Pharmaceutical scientists at the National University of Singapore (NUS) have developed a method that can measure the kinetic efficiency of an enzyme against more than 200,000 potential peptide ...

Proteases are involved in the regulation of a wide variety of essential physiological processes, and their dysregulation has been implicated in a number of disorders including cardiovascular disease, ...

Researchers from the University of Massachusetts, Amherst, say they have made an important discovery on how cells handle stress. Using bacterial cells, the team found that a damage-repairing enzyme, ...