The project to be carried out at IRB Barcelona has been awarded €2M to address an understudied mutation type known as structural variants. Using machine learning approaches, as well as innovative ...

The mechanism unveiled triggers a mutation fog, causing hundreds of mutations in each tumor, which spread through the genome of lung, head-and-neck and breast cancers. Researchers have identified the ...

Hypermutation is an unusual occurence that can lead to many nearby mutations at once, severely damaging our genetic material and potentially causing cancer. Researchers from IRB Barcelona's Genome ...

Barcelona, May 26, 2022,- Cancer therapy increasingly relies on a personalised approach, where genetic changes in an individual tumour can be used to determine the best therapeutic strategy. In many ...

Anna M. Supek, 90, of Manifold, South Strabane Township, died Friday, January 10, 2014, in Orange Regional Medical Center, Middletown, N.Y., with her loving family by her side. She was born July 22, ...

Researchers have identified critical spots on the genome where gene editing could cause an unwanted response, and they provide recommendations for safer approaches. CRISPR/Cas9 is a commonly used, ...

Just as species adapt over generations, our body's cells accumulate DNA changes throughout life. Most are harmless, yet a few "driver" mutations give a cell a competitive edge and can spark cancer.