How do we think, feel, remember, or move? These processes involve synaptic transmission, in which chemical signals are transmitted between nerve cells using molecular containers called vesicles. Now, ...

Interactions of two voltage-gated calcium channels and a pump enable separate control of exocytosis and endocytosis at chemical synapses. Chemical synapses transmit information within the nervous ...

Prof. Fang-Jen S. Lee's team at National Taiwan University has discovered that an intermediate cellular metabolism molecule, glycerol, regulates the localization and function of the Golgi protein Imh1 ...

Scientists haven’t had a precise way to arrange and study surface-bound extracellular vesicles and particles (EVPs) as they guide cell behavior. Researchers developed LEVA, which uses patterned ...

Imaging live cells is key to reveal their inner workings, dynamics, and function. Current technological advances in confocal imaging can benefit from novel fluorescence labeling strategies and ...

Extracellular vesicles and particles are central to how cells communicate, especially in cancer, where they help shape metastasis and treatment resistance. However, most existing methods analyze ...

A new study by researchers at Karolinska Institutet (KI) demonstrates how extracellular vesicles (EVs) activate the immune system in mice and seem to make their tumors sensitive to a checkpoint ...

Researchers developed an AI-assisted nanotweezer platform that rapidly traps thousands of milk-derived extracellular vesicles ...

Video depiction of vesicle fusion and tethering. In the active zone in the central left of the video, docked vesicles (dark blue) fuse with the membrane, releasing their contents and being quickly ...