The Seegar Lab used advanced cryogenic electron microscopy techniques to visualize the structure of the ADAM17 enzyme bound to its regulator protein, iRhom2, and identify key elements vital for its ...

When a protein folds, its string of amino acids wiggles and jiggles through countless conformations before it forms a fully folded, functional protein. This rapid and complex process is hard to ...

Structural biologists Jan Steyaert and Els Pardon have developed protein-imaging techniques using nanobodies. Biologists Jan Steyaert and Els Pardon are using miniature versions of antibodies – ...

Biologists can image proteins using electron and atomic force microscopes. They can visualize the three-dimensional structure of proteins--amino-acid sequences folded in complicated ways--by using X ...

Scientists organize millions of proteins by shape, as predicted by AI, revealing 700,000 new families and some shapes unique ...

For his work to help capture and view dynamic small-scale behaviors of biomolecules that have gone unseen – and which are critical to applications like drug development – Zhuoran Qiao has been awarded ...

On Wednesday, the Nobel Committee announced that it had awarded the Nobel Prize in chemistry to researchers who pioneered major breakthroughs in computational chemistry. These include two researchers ...

In the wee hours of an October morning, David Baker, a protein biologist at the University of Washington (UW), received the most-awaited phone call in a scientist’s career. Halfway around the world, ...

What they saw The Seegar Lab used advanced cryogenic electron microscopy techniques to visualize the structure of the ADAM17 enzyme bound to its regulator protein, iRhom2, and identify key elements ...