Scientists have known for decades that opioids relieve pain by binding to molecular switches in the brain called mu-opioid receptors. What they didn't know—until now—was exactly what happens next. A ...
This confocal microscope image shows midbrain neurons (red) co-expressing the mu-opioid receptor (Oprm1, white) and cannabinoid receptor 1 (Cnr1, green). The interaction of these two reward pathways ...
Scientists have known for decades that opioids relieve pain by binding to molecular switches in the brain called mu-opioid (pronounced "mew-opioid") receptors. What they didn't know - until now - was ...
Two different versions of the mu-opioid receptor within a cellular membrane illustrate how the receptor changes its conformation to send a signal into the cell. Scientists captured six high-resolution ...
The Nature Index 2025 Research Leaders — previously known as Annual Tables — reveal the leading institutions and countries/territories in the natural and health sciences, according to their output in ...