A recent study published in Engineering delves into the complex mechanisms of drug addiction, highlighting the crucial role of astrocytic G protein-coupled receptors (GPCRs). This research offers ...
G protein-coupled receptors (GPCRs) represent the largest family of cell surface receptors, orchestrating a vast array of physiological responses by transducing extracellular signals into ...
The discovery of G protein-coupled receptor (GPCR) heteromers has revealed a new level of complexity in their functional characteristics. This review explores a variety of methodologies and live cell ...
New study shows that targeting an oft-drugged family of cell membrane receptors with biased modulators can expand potential drug targets and reduce side effects.
This new article publication from Acta Pharmaceutica Sinica B, discusses allosteric modulation of G protein-coupled receptors as a novel therapeutic strategy in neuropathic pain. Neuropathic pain is a ...
New research led by the University of Minnesota Medical School demonstrates that molecules acting as "molecular bumpers" and ...
Domain Therapeutics, a clinical-stage biopharmaceutical company, has appointed Jean-Marie Cuillerot, M.D., as Chief Medical ...
Scientists have visualized for the first time how opioids such as loperamide and the antidote naloxone engage a key brain ...