Demercado, Murray, Michael Carter and Bam Knight combined to rush for 168 yards. That's a good sign for the Cardinals considering veteran James Conner (foot) is out for the season and backup Trey Benson (knee) will miss at least three more games.

In a moment of frustration, Arizona Cardinals head coach Jonathan Gannon let the moment get to him. The typically stoic leader of the Cardinals was spotted by cameras as fired up and passionate as ever after watching running back Emari Demercado cost Arizona six points,

Kyler Murray walked into the locker room with trainers after a fumble that appeared to be a result of miscommunication.

Early in the fourth quarter, Cardinals running back Emari Demercado dropped the football before waltzing into the end zone on a wide-open touchdown, which empowered the Titans offense to march 80 yards for their first touchdown in two weeks. Then, down nine points, the Titans turned a Cardinals interception -- into a Tennessee touchdown.

After four weeks of imbalanced football, that trend continued for the Cardinals in their Week 5 22-21 loss to the Tennessee Titans. The Cardinals were up two possessions late in the game before the Titans fought back and took things down to the final seconds before kicking a game-winning field goal.

Cam Ward and the Tennessee Titans ended their losing streak after beating the Arizona Cardinals by a solitary point in Week 5.

For the Mets, Arenado could fill a long-standing void at third base. Surrounded by stars such as Juan Soto, Francisco Lindor and potentially Pete Alonso, Arenado would not be counted on as a middle-of-the-order bat, but rather as a stabilizing defensive presence with the potential for offensive upside.

The St. Louis Cardinals went 78-84 and missed the postseason for the third straight year in 2025. This was also their second losing season in the last three yea