And Michigan State basketball's surprising season rolled on Friday night with yet another comeback victory. With a shortened rotation, the No. 2 seed Spartans found a way to overcome the swarming defense and aggression of No.

The 2025 NCAA Men’s Basketball Tournament continues on Friday, March 28 with more Sweet 16 action, this time in the South Region, where the 2 seed Michigan State Spartans battle the 6 seed Ole Miss Rebels at State Farm Arena in Atlanta.

Analyzing Friday’s Ole Miss vs. Michigan State odds and lines, with college basketball expert picks, predictions and best bets.

Jace Richardson scored 24 points and Michigan State surged past Mississippi in the second half for a victory on Friday in the March Madness Sweet 16.

Since 1939, never in the history of the NCAA tournament have rivals Michigan and Michigan State basketball met in March Madness.

The Spartans trailed 48-39 with 12:15 to go and went on a 14-2 run to take a 53-50 lead. But as soon as Michigan State jumped out to that three-point lead, Ole Miss' Sean Pedulla tied the game with a 3-pointer. He led all scorers with 24 points. MSU's Jase Richardson had 20, while Coen Carr had 15 and a highlight-reel steal and dunk.

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Tom Izzo wants to get back to a Final Four and beyond. Before that, Michigan State basketball must get past a Mississippi team that resembles his own.