A recent publication presents the results of a clinical trialclinical trial Very carefully planned experiments designed to ...

This study moves MutLβ from being a semi-unknown quantity in somatic expansion to a defined member of the responsible team.

6 min read | A new study suggests that reduced awareness of symptoms, known as anosognosia, may appear even in the earliest ...

This gene contains the instructions for making the huntingtin proteinhuntingtin protein The protein produced by the HD gene..

Huntington’s disease (HD) involves the loss of cells in the striatum, an area of the brain that plays important roles in movement, cognition, and behaviour. For decades, researchers have been ...

The Huntington’s Disease Youth Organization (HDYO) is an international non-profit dedicated to supporting, educating, and empowering young people up to the age of 35 who are impacted by Huntington’s ...

In plain language. Written by scientists. HDBuzz has ramped up to match the accelerating pace of Huntington’s disease research. April 2025 brought us insight on somatic expansion, replacing lost brain ...

In plain language. Written by scientists. A new study from researchers at Thomas Jefferson University delves into the details of how genetic modifiers of Huntington’s disease work. Both PTC ...

On 25th June 2024, Wave Life Sciences shared the results of their SELECT-HD clinical trialclinical trial Very carefully planned experiments designed to answer specific questions about how a drug ...

⏱️ 9 min read |New research in a HD mouse model points to a key culprit: a small fragment called HTT1a. Lowering HTT1a levels successfully delayed disease signs in mice that model HD, perhaps shaping ...

Hello from Palm Springs! The HDBuzz team are here and ready to report on all of the exciting science that we are going to hear over the next 3 days from HD experts who have travelled from all over the ...

SOM3355 is an investigational therapy aimed at managing multiple symptoms of Huntington’s disease (HD) and recently crossed two key regulatory milestones. In September, the European Medicines Agency ...