A recent publication presents the results of a clinical trialclinical trial Very carefully planned experiments designed to ...

This study moves MutLβ from being a semi-unknown quantity in somatic expansion to a defined member of the responsible team.

6 min read | A new study suggests that reduced awareness of symptoms, known as anosognosia, may appear even in the earliest ...

This gene contains the instructions for making the huntingtin proteinhuntingtin protein The protein produced by the HD gene..

Huntington’s disease (HD) involves the loss of cells in the striatum, an area of the brain that plays important roles in movement, cognition, and behaviour. For decades, researchers have been ...

The Huntington’s Disease Youth Organization (HDYO) is an international non-profit dedicated to supporting, educating, and empowering young people up to the age of 35 who are impacted by Huntington’s ...

In plain language. Written by scientists. HDBuzz has ramped up to match the accelerating pace of Huntington’s disease research. April 2025 brought us insight on somatic expansion, replacing lost brain ...

In plain language. Written by scientists. A new study from researchers at Thomas Jefferson University delves into the details of how genetic modifiers of Huntington’s disease work. Both PTC ...

This week, we heard an update from Roche about their huntingtin-lowering therapy, tominersen, currently being tested in the GENERATION HD2 trial. An independent data monitoring committeemonitoring ...

People who develop Huntington’s disease (HD) are born with the genetic change that causes the disease. So why does it take decades, usually around 40 to 50 years, for the symptoms of the disease to ...

A BLA, or Biologics Licensing Application, is the formal dossier of information that a company uses to request permission to market a biologic, which is a therapy created from living organisms, like ...

In an update from uniQure, they report that their experimental gene therapy, AMT-130, has the potential to slow Huntington’s disease progression in key clinical study. HD is caused by a faulty copy of ...