Engineered bacteria reprogram tumor macrophages and direct copper into cancer cells, triggering cell death and systemic immunity without damaging healthy tissue.

Cellular and molecular regulators play a pivotal role in non-neoplastic immune-mediated diseases, where the immune system ...

To grow, cancer tumors must hijack the immune system for their needs. One of the main tricks that most tumors use is to manipulate a type of immune cell called a macrophage, causing it to protect the ...

T-cell exhaustion and pre-existing T-cell immunity in circulation as predictive biomarkers for immunotherapy in NSCLC patients. Monitoring PD-L1 expression in cancer-associated macrophage-like cells ...

Creative Biolabs has developed a new series of research toolkits for use in the discovery and advancement of immunotherapy research.

New findings reveal how cancer manipulates immune pathways and highlight therapeutic strategies to unleash T-cells against even the most resistant tumors. Study: Cancer cells impair monocyte-mediated ...

In a surprising twist on cellular metabolism, scientists have uncovered a noncanonical role of the metabolic enzymePHGDH in shaping immune responses within breast cancer microenvironment. Acting from ...

Researchers at the University of Calgary studying a lethal lung disease called pulmonary fibrosis have found neurons, which ...

Five signaling subtypes identified by NMF clustering. Subtype 5 (high APsig) correlates with immune-rich "hot" tumors, while Subtype 2 (low APsig) exhibits metabolic reprogramming and hypoxia. High ...