Researchers in Australia have reprogrammed the RNA-cutting enzyme PspCas13b to destroy the fusion transcripts that drive many ...
Six patients with glycogen storage disease type Ia have received a single infusion of BEAM-301, an in vivo base editor ...
Researchers built a three-layer human blood-vessel model that shows how fibroblasts amplify the vascular pathology of ...
Researchers have used CRISPR-Cas9 to remove CD28 from donor T cells and prevent fratricide before equipping them with ...
Minutes ago, French and Italian researchers published a gene-editing strategy using adenine base editors to precisely repair two of the most common severe β-thalassaemia mutations, restoring adult ...
Scribe Therapeutics is preparing to take its first cardiometabolic programme into the clinic in mid-2026, positioning STX-1150 as a potentially durable alternative to today’s chronic lipid-lowering ...
What is prime editing and what is it used for? Prime editing was described initially by the laboratory of Dr. David Liu in 2019 (1). This powerful tool combines the DNA-scanning and ...
A hybrid CRISPR design pipeline improves the predictability of genome editing outcomes in mouse embryos. By favouring microhomology-mediated end joining (MMEJ) and validating guides in stem cells, the ...
A genome-wide CRISPR-Cas9 screen to identify transcription factor SOX2 as a critical regulator of PROM1, the gene encoding CD133, in glioblastoma stem cells. Knocking out SOX2 reduced CD133 expression ...
Great to see our founder Jens-Ole Bock speaking at this week's CRISPR Gene Editing Hands-on Workshop... Clinical: Expanded Access Takes SNIPR001 Beyond... CRISPR-Cas base editing altered HTT RNA ...
Six patients with glycogen storage disease type Ia have received a single infusion of BEAM-301, an in vivo base editor designed to correct the R83C... Researchers built a three-layer human ...
Life Edit Therapeutics was recently acquired and is now a subsidiary of ElevateBio. The company develops multiple novel gene-editing technologies, including CRISPR-Cas, base editing and ...
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