This valuable study substantially improves the phylogenetic framework for Kinetoplastea through greatly expanded sampling of free-living neobodonids; the phylogenomic analyses provide convincing ...

Biochemical and electrophysiological approaches show that the amphetamine derivative ECSI#6 is an uncompetitive inhibitor of the serotonin transporter and thus the first ever characterized ligand of a ...

eLife reviews research in which approaches from the physical sciences are used to provide insights into the properties of biological systems and processes. Learn more about what we review and sign up ...

eLife reviews plant biology research including development, epigenetics, genomics, signalling, metabolism and plant-microbe interactions. Learn more about what we review and sign up for the latest ...

Researchers have investigated the molecular mechanisms that cause fewer red blood cells to be produced during iron deficiency. Red blood cells use a molecule called hemoglobin to transport oxygen ...

Add a comment + Open annotations. The current annotation count on this page is being calculated. Researchers have provided new insights into the evolutionary origin of sideways walking in crabs. Their ...

This is a valuable contribution to our understanding of how some bacteria can transport sterols from the cytoplasm to the outer membrane. Though much remains to be tested and explored, the data and ...

A project to repeat experiments from high-impact papers in cancer biology found that the effects observed in replications were frequently weaker than, or inconsistent with, the effects reported in the ...

Crystal structures of γ-protocadherin cell-cell recognition dimers reveal the determinants of clustered protocadherin homophilic specificity and cis interaction region structures alongside mutagenesis ...

This study examines an interplay between synaptic mitochondria and glutamate receptor exocytosis in C. elegans. Collectively, the solid results support the idea that mitochondrial function influences ...

A family of proteins called Toll receptors, best known for their role in the immune system, also enable the brain to change its structure in response to experience. Everything that you experience ...

The CRISPR-Cas system in some bacteria helps to form an effective barrier to invading viruses. Just as humans are susceptible to viruses, bacteria have their own viruses to contend with. These viruses ...